Operationalisation of the Sterile Insect Technique against Aedes vectors of dengue in Réunion - OpTIS

The objective of the OpTIS project is to demonstrate the effectiveness of the boosted Sterile Insect Technique (SIT) in reducing populations of mosquitos of the Aedes genus and preventing the transmission of dengue and chikungunya.
Field visit to identify sentinel larval habitats to be monitored in the OpTIS project © J. Bouyer, ÁùºÏ²Êͼ¿â
Field visit to identify sentinel larval habitats to be monitored in the OpTIS project © J. Bouyer, ÁùºÏ²Êͼ¿â

Field visit to identify sentinel larval habitats to be monitored in the OpTIS project © J. Bouyer, ÁùºÏ²Êͼ¿â

Innovative dengue control: a mosquito sterilisation technique tested on a large scale

Teams from ÁùºÏ²Êͼ¿â and IRD are developing the boosted Sterile Insect Technique (SIT) against Aedes mosquitoes and dengue virus transmission in Réunion. Following successful field trials of classical SIT in Duparc (Sainte-Marie municipality) in 2021-2022 (TIS2B project) and boosted SIT in Vincendo (Saint Joseph municipality) in 2021 (REVOLINC project), the goal now is to demonstrate the effectiveness of this approach on a large scale over two years in a 200-hectare urban area in Saint Joseph in the south of the island.

A multidisciplinary scientific approach to validate the effectiveness of boosted SIT in Réunion

The goal of this project, coordinated by ÁùºÏ²Êͼ¿â and conducted in partnership with IRD, is to assess the impacts of boosted SIT: (i) entomological, on target species (reduction of Aedes mosquito density); (ii) environmental, on non-target fauna; (iii) epidemiological, on the transmission of dengue and chikungunya viruses; and (iv) sociological, on the acceptability of this approach. A communication strategy is being implemented with support from Saint Joseph town council to engage the beneficiary populations and keep them regularly informed with transparent updates.

The project steering committee includes all partners, ARS Réunion, and the Nature Océan Indien association.

This large-scale intervention will deliver the scientific evidence required for the technical and economic development of a start-up based in Réunion, which will be responsible for the operationalisation of boosted SIT in Réunion from the third year onwards.

Furthermore, as part of this project, the acquisition of an irradiator to develop local capacities for intervention and treatment of mosquitos, then other insect vectors and pests, will complement the sustainable infrastructure already in place for the promotion and use of SIT on the island, with potential impacts across the Indian Ocean region and towards Europe.

Contract partners of OpTIs project :
- Institut de recherche pour le développement (IRD) ;
- Centre d'Etude Technique Apicole 974 (subcontractor) ;
- Unité analytique du CYROI (subcontractor).
Associate partners:
- Ecole Hautes Etudes de Santé Publique de Rennes ;
- Agence Internationale de l’Energie Atomique (Vienna, Austria) ;
- Saint Joseph town hall.